David A. SinclairPhD · Professor of Genetics, Harvard Medical School
Yes, and repeat it
What it rests onMethylation-clock research and his own biotracking practice.
Source: lifespanpodcast.com ↗
Crossfire
Should I get a biological age test?
What the experts say
David A. SinclairPhD · Professor of Genetics, Harvard Medical School
Matt KaeberleinPhD · biogerontologist
No, do not buy one
What it rests onTest-retest and validation problems with the clocks, and the absence of regulatory oversight of the consumer products.
Source: podcasters.spotify.com ↗
Overview
Both address a general adult population. The one difference that matters is timing: the Sinclair position is from 2022, when the consumer market barely existed, and the Kaeberlein position is from 2025, after it did. The three-year gap is part of the disagreement.
Where they agree
Both think measurement is the right instinct. Neither says track nothing. They disagree about whether this particular product measures anything.
What would settle it
A consumer clock with published test-retest reliability at the individual level and a prospective association with a hard outcome. Kaeberlein has separately named one test as the most promising he has seen, which is not recorded as a claim here because the source establishes the name and not his verdict; if that qualification is real it will move this question.
Practice does not pick a winner here
You do, and your call is dated, kept, and yours to change. Follow the people you already trust and what they publish turns into a short daily practice.
- Record where you land on this, and change your mind later without losing the history
- The 2 practices that follow from this question, graded and linked to the source
- Everything else these people publish, read and graded, in one place
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