Christopher D. GardnerPhD · nutrition scientist, Stanford Prevention Research Center
No. Once both diets exclude added sugar and refined grain, the carbohydrate level stops deciding the outcome.
What it rests onA 12-month randomised trial in 609 adults where a healthy low-fat and a healthy low-carbohydrate arm produced median weight changes of 5.3 kg and 6.0 kg with no significant difference, and where neither a prespecified genotype pattern nor baseline insulin secretion moderated the effect. A second trial in prediabetes and type 2 diabetes found ketogenic and Mediterranean-plus arms did not differ on HbA1c at 12 weeks. He concedes a small behavioural edge to low-carbohydrate eating (gar-lowcarb-edge) and locates it in cheating patterns rather than metabolism.
Source: jamanetwork.com ↗
