Practiceby Lab 10 Get started ›
Crossfire

For losing weight, does it matter whether I cut fat or cut carbs?

What the experts say

Nina TeicholzPhD · investigative science journalist and author

Cut carbs. In head-to-head trials the low-carbohydrate arm has nearly always lost more.

What it rests onThe low-fat preference rests on a 1970s hypothesis about fat's nine calories per gram. Multiple large long-term controlled experiments could not confirm that a low-fat diet produced significant weight loss, and in head-to-head trials with low-carbohydrate diets the latter "have nearly always led to more weight loss". She adds that low-fat diets reliably lower HDL cholesterol and raise triglycerides, and that the US Dietary Guidelines quietly dropped "low-fat" from their recommendations in 2015 without telling the public.

Source: pmc.ncbi.nlm.nih.gov ↗
Christopher D. GardnerPhD · nutrition scientist, Stanford Prevention Research Center

Neither. Once both diets exclude added sugar and refined grain, the macronutrient split stops deciding the outcome.

What it rests onA 12-month randomised trial in 609 adults comparing a healthy low-fat with a healthy low-carbohydrate diet, both built under deliberate equipoise, produced median weight changes of 5.3 kg and 6.0 kg with no significant difference, and neither a prespecified genotype pattern nor baseline insulin secretion moderated the result. He concedes a small behavioural edge to low-carbohydrate eating (gar-lowcarb-edge) and locates it in cheating patterns rather than metabolism. His own 2007 A TO Z trial found the Atkins arm lost the most weight and he has never withdrawn it (gar-lowcarb-legitimate).

Overview

Teicholz is mostly addressing people who are already overweight, pre-diabetic or diabetic, and she says so: her stronger claims are explicitly scoped to people with carbohydrate intolerance. Gardner's DIETFITS enrolled adults with a BMI of 28 to 40 without diabetes.

The trials she leans on include arms without the food-quality floor Gardner's design imposed on both arms, which is the crux: he argues the difference disappears once both diets exclude added sugar and refined grain, and she does not accept that the comparison was fairly built.

Where they agree

Substantial and easy to miss. Both reject calorie counting as the operative lever, both treat added sugar and refined flour as primary problems, both think the low-fat era failed, and both say adherence is what decides an outcome. Gardner's own A TO Z result is the single best trial evidence for her side and he keeps publishing it.

What would settle it

For her: a well-powered head-to-head with genuine equipoise, hard endpoints, and a quality floor on both arms, in a metabolically ill population rather than in healthy volunteers. For him: the same trial with a different result. Both sides have effectively specified the same missing study, which is the most useful thing this entry surfaces.

Practice does not pick a winner here

You do, and your call is dated, kept, and yours to change. Follow the people you already trust and what they publish turns into a short daily practice.

Get started

Free to sign up and use. We do not ask for a card.